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Clinical Trials Unit
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Where Research & Transparency Converge; Your Trusted Partners
Brief Introduction To The Clinical Trial Unit
Dr. Akbar Niazi Teaching Hospital (ANTH) a licensed Clinical Trial Unit (CTU) is dedicated to developing systems and processes for conducting high quality clinical trials across various medical domains, including pharmaceuticals, alternative therapies, and medical devices in Pakistan. ANTH-CTU can contribute to improving drug accessibility, fostering collaboration with international research organizations and targeted companies, and advancing healthcare practices both within Pakistan and globally.
Overview
Director’s Message (CTU)
I extend a warm welcome to you on behalf of our Clinical Trial Unit that is committed to bringing innovations in Phase 3 and 4 clinical trials. Our mission is to advance medical research, find new treatments, and improve patient care.
With a dedicated team and advanced facilities, we are emerging as a beacon of hope for numerous patients and researchers. Navigating through our site, you will discover the depth and width of our expertise and ongoing trials as well as the impact of our work. We welcome collaboration with pharmaceutical companies, academic institutions, and fellow researchers to make a real difference. Whether you are a researcher, potential collaborator, or just curious about healthcare's future, I invite you to explore, engage, and envision possibilities with us. Let us continue to make positive contributions to the field of medicine through impactful clinical research.
Dr. Areej Neyazi, Director CTU
Facilities & Services
ANTH-CTU includes clinical, equipment, and administrative facilities.
The Facility Features
Dedicated rooms for randomization, screening, and consent room and vital rooms for medical monitoring. Key administrative areas. Observation and post-observation spaces. Essential equipment like oxygen supply, vacuum systems, and infusion pumps. Facilities for handling protocol-related specimen collection and management. Exclusive workspace for investigators during research clinics. Nutrition support available as per study protocol, accommodating fasting and long-term stay requirements.
Drug Supply Management
Our Clinical Trials Unit features secure and temperature-controlled storage facilities including -80°C freezers to ensure the integrity of investigational products, medications, and biological samples throughout the trial duration.
Laboratory Services
The CTU houses a fully equipped laboratory and has certification of ISO 9001:2015 and ISO 15189:2012 the advanced analytical instruments, allowing for prompt and accurate analysis of biological samples, contributing to efficient trial conduct and data generation.
Data Management & Analysis
We have a sophisticated data management center equipped with the latest technology to ensure secure, efficient, and compliant handling of trial data, from collection to analysis.
We utilize advanced systems and statistical methods to support high-quality research outcomes and reporting.
Quality Assurance & Safety
The CTU ensures that all clinical trial processes meet regulatory standards and ICH-GCP guidelines. Regular audits and inspections are conducted to maintain data integrity and compliance throughout the study.
Regulatory & Ethics Compliance
We ensure all clinical trials meet national and international regulatory as well as ethical standards. Our team manages approvals, documentation, and ongoing compliance in accordance with ICH-GCP guidelines, ensuring patient safety, transparency, and regulatory adherence throughout the study lifecycle.
Observational Studies
Our Clinical Trials Unit conducts high-quality observational studies to generate real-world evidence that supports clinical decision-making and improves patient care. These studies are conducted under strict ethical guidelines and regulatory standards to ensure reliable and meaningful results.
Clinical Trials - Current Status
1. Phase 3 Open-label Study -HCV (FDC Therapy)
CRO: IQVIA
PI: Prof. Dr. Rizwan Aziz Qazi
Status: Ongoing Enrollment
Sponsor : Atea pharmaceuticals
2. MB12-C-02-24 -Pembrolizumab Biosimilar vs Keytruda® in NSCLC
CRO: ICON
PI: Dr. Ali Wajid
Status: Ongoing Enrollment
Sponsor : mAbexience Research SLU
1. Leucodepletion Filters Study in Multi-Transfused Patients
Sponsor: ANTH-CTU
PI: Dr. Aliya Batool
Status: Completed
Outcome:
35 filters used
Conducted with BMT department
Infectious Diseases
Phase 2b HDV Study (VIR-3434 + VIR-2218) -IQVIA
Tuberculosis Phase 3 MDR Study -IQVIA (Queries submitted)
A. baumannii Infection Study (HABP/VABP/BSI) -Tigermed
Oncology / Immunology
Phase 3 NSCLC (PD-L1 High Expression) -Tigermed
Natalizumab vs Tysabri® (Multiple Sclerosis) -SMCT
Pembrolizumab Comparator Study (NSCLC) -Tigermed
Nephrology / Metabolic
CKD Study (Obese ± T2DM) -IQVIA
Proteinuric Glomerular Disease Study -Tigermed
Roxadustat (HIF Inhibitor) Study -ANTH-GETZ
Liver / MASH
MASH / MASLD Study (Efimosfermin alfa) -IQVIA
Chronic Liver Disease (CLD) Study -Tigermed
Hematology & Rare Diseases
Hemophilia B Study -Orci Trials (Questionnaire submitted)
Thalassemia Phase III Study -MCT CRO (Feasibility done)
Critical Care / Sepsis
Neonatal & Pediatric Sepsis Feasibility -IQVIA
Sepsis / Septic Shock Feasibility -IQVIA
Other Studies
Yeast Protein Nutrition Study (Maternal & Infant) -Tigermed
ALS Repurposed Drug Study -Continuum Research
Skin Prick Allergy Study (Device) -Trials 360
MASH Feasibility Study -Dimension Research
PH-ILD Management Practices Study -IQVIA
Critical Limb Ischemia Study -Tigermed
Have a Question? Get In Touch
Have a question? Want to participate in a Clinical Trial? Give us a call or send an email to contact the ANTH-CTU.
General Information
Satra Meel, Main Murree Road,
Bhara Khu, Islamabad
Phone: +92-51-111464632
Email: info@anth.pk
Clinical Trial Unit
Dr. Areej Neyazi - Director CTU
Phone: +92-51-8153000-5
Ext: 708
Email: Info.clinicalresearch@danthospital.com
Working Hours
Monday – Friday : 9:00 AM - 5:00 PM
Saturday : 9:00 AM - 5:00 PM
Collaborations
